Doctor of Philosophy, Chung Yuan Christian University, 2012
Master of Science, University of Santo Tomas – Manila, Philippines, 2005
Bachelor of Science, University of Santo Tomas – Manila, Philippines, 1997
Research Highlights
Discovery of secondary metabolites from Philippine plants with anti-diabetic activities
Discovery of Philippine plant constituents that inhibit the formation of amyloid-beta plaques in brain of Zebra fish
Discovery of both anti- and angiogenic agents from natural products
Discovery of biologically active peptides from venoms of marine and land animals
Research Interests
Isolation natural products
Neurodegenerative diseases
Angiogenesis
Bioactive peptide isolation
Courses Handled
Major Recognitions
Professional Activities
Courses Handled
Major Recognitions
Professional Activities
Member,Natural Product Society of the Philippines
Selected Publications
Selected Publications
Antibacterial Activity and Concentration Dependent Modulation of Angiogenesis of the Saponins of Scheffleraluzoniensis (Original Research Article) Covarrubias, J.L.A., Macabeo, A.P.G., Villaflores, O.B., Knorn, M., Kohls,P., and Bayquen, A.V.Research Journal of Pharmaceutical, Biological and Chemical Sciences. 418-422. March-April 2015.
Easy expression of the C-terminal heavy chain domain of botulinum neurotoxin serotype A as a vaccine candidate using a bi-cistronicbaculovirus system (Original Research Article) Villaflores O.B., Hsie C.M., Teng C.Y., Chen Y. J., Wey J.J., Tsui P.Y., Shyu R.H., Tung K.L., Yeh J.M., Chiao D.J. and Wu T.Y. Journal of Virological Methods. 189(1): 58-64. April 2013.
Effects of curcumin and demethoxycurcumin on amyloid-b precursor and tau proteins through the internal ribosome entry sites: A potential therapeutic for Alzheimer’s disease (Original Research Article) Villaflores O.B., Chen Y.J., Chen C.P., Yeh J.M., and Wu T.Y. Taiwanese Journal of Obstetrics and Gynecology. 51(4): 554-564. December 2012.